This article is based on Mayo Clinic’s content.

What is prostatic hyperplasia?

Benign prostatic hyperplasia, also called “enlarged prostate gland,” is a common condition as men get older. Enlargement of the prostate gland can cause annoying urinary symptoms, such as blocking the flow of urine from the bladder. It can also cause bladder, urinary tract or kidney problems.

There are several effective treatments for an enlarged prostate gland, including medications, minimally invasive therapies and surgery. To choose the best option, you and your doctor will consider the symptoms, the size of the prostate, other health disorders you may have and your preferences.

Do you want to know more about benign prostatic hyperplasia?

We recommend that you continue reading the Diseasepage of the NHS for the public.

What mushrooms have useful properties in prostatic hyperplasia?

Mushrooms selected to support this condiiton help to decrease the growth of the prostate and help to regulate the immune system.


Shown to Inhibit the growth of the prostate

Reishi-containing formulations can support benign prostatic hyperplasia byrducing 5α-reductase, an enzyme responsible for hormonal changes.

After analyzing up to nineteen species of mushrooms, Reishi was by far the most powerful in reducing the capacity of the 5α-reductase.This enzyme, then unregulated is responsible for causing the enlargement of the prostate.


  1. Bandara AR, Rapior S, Bhat DJ, Kakumyan P, Chamyuang S, Xu J, Hyde KD (2015) Polyporus umbellatus, an edible-medicinal cultivated mushroom with multiple developed health-care products as food, medicine and cosmetics: a review. Cryptogamie, Mycologie 36, 3-42.
  2. Bartsch G, Rittmaster RS, Klocker H (2000) Dihydrotestosterone and the concept of 5α-reductase inhibition in human benign prostatic hyperplasia. Eur. Urol., 37, 367-380.
  3. Fujita R, Liu J, Shimizu K, Konishi F, Noda K, Kumamoto S, Ueda C, Tajiri H, Kaneko S, Suimi Y, Kondo R (2005) Anti-androgenic activities of Ganoderma lucidum. Journal of Ethnopharmacology 102, 107-12.
  4. Grant P, Ramasamy S (2012) An update on plant derived anti-androgens. International Journal of Endocrinology and Metabolism 10, 497-502.
  5. Kuok KY, Ly H (2004) Herbal composition for prostate conditions. United States patent application US20040142001A1. 2004.07.22.
  6. Liu J, Kurashiki K, Fukuta A, Kaneko S, Suimi Y, Shimizu K, Kondo R (2012) Quantitative determination of the representative triterpenoids in the extracts of Ganoderma lucidum with different growth stages using high-performance liquid chromatography for evaluation of their 5α-reductase inhibitory properties. Food Chemistry 133, 1034-1038.
  7. Liu J, Shimizu K, Konishi F, Kumamoto S, Kondo R (2007b) The anti-androgen effect of ganoderol B isolated from the fruiting body of Ganoderma lucidum. Bioorganic & Medicinal Chemistry 15, 4966-4972.
  8. Liu J, Shimizu K, Konishi F, Noda K, Kumamoto S, Kurashiki K, Kondo R (2007a) Anti-androgenic activities of the triterpenoids fraction of Ganoderma lucidum. Food Chemistry 100, 1691-1696.
  9. Liu J, Tamura S, Kurashiki K, Shimizu K, Noda K, Konishi F, Kumamoto S, Kondo R (2009) Anti-androgen effects of extracts and compounds from Ganoderma lucidum. Chemistry and Biodiversity 6, 231-243.
  10. Nahata A, Dixit VK (2012) Ganoderma lucidum is an inhibitor of testosterone-induced prostatic hyperplasia in rats Andrologia 44, 160-174.
  11. Pérez Guerra Y, Molina Cuevas V, Oyarzábal Yera A, Mas Ferreiro R (2011) Tratamiento farmacológico en la hiperplasia prostática benigna. Pharmacological treatment of the benign prostatic hyperplasia. Editorial Ciencias Médicas.
  12. Zeng Q (2014) Traditional Chinese medicine composition for treatment of benign prostatic hyperplasia and its preparation method and application. China patent application CN103520638A. 2014.01.22.